Title of article :
Applications of Baylis–Hillman chemistry: enantioselective synthesis of (−)-methyl 3-aryl-2-methylene-3-(prop-2-yn-1-yloxy)propanoates via chiral leaving group strategy
Author/Authors :
Deevi Basavaiah، نويسنده , , Nagaswamy Kumaragurubaran، نويسنده , , Duddu S Sharada، نويسنده , , Ravi Mallikarjuna Reddy، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
Asymmetric synthesis of (−)-methyl 3-aryl-2-methylene-3-(prop-2-yn-1-yloxy)propanoates in 25–40% enantiomeric purities via the reaction of methyl (2Z)-3-aryl-2-(bromomethyl)prop-2-enoates with prop-2-yn-1-ol in the presence of quinidine is described.
Keywords :
chiral leaving group , methyl 3-aryl-2-methylene-3-(prop-2-yn-1-yloxy)propanoates , Baylis–Hillman chemistry
Journal title :
Tetrahedron
Journal title :
Tetrahedron
