Title of article
Diastereoselective cyclopropanation of cyclic enones with methyl dichloroacetate anion
Author/Authors
Ana Escribano، نويسنده , , Concepcion Pedregal، نويسنده , , Rosario Gonz?lez، نويسنده , , Alejandro Fernandez-Martinez، نويسنده , , Keith Burton، نويسنده , , Gregory A. Stephenson، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
5
From page
9423
To page
9427
Abstract
The reaction of α,β-unsaturated cyclic ketones with methyl dichloroacetate anion in the presence of DBU leads to the corresponding bicyclic chlorocyclopropanes in a highly diastereoselective fashion. In the cases of 2-cyclopentenone and 2-cyclohexenone the reaction affords exclusively the endo-Cl isomer.
Keywords
Cyclopropanation , Diastereoselectivity , Michael initiated ring closure , cyclic enones
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082559
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