Title of article :
Modified nucleosides. A general and diastereoselective approach to N,O-psiconucleosides
Author/Authors :
Daniela Iannazzo، نويسنده , , Anna Piperno، نويسنده , , Venerando Pistarà، نويسنده , , Antonio Rescifina، نويسنده , , Roberto Romeo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
An efficient reaction route towards the new class of N,O-psiconucleosides has been designed, based on the 1,3-dipolar cycloaddition of C-[(tert-butyldiphenylsilyl)oxy]methyl-N-methyl nitrone with ethyl 2-acetyloxyacrylate, followed by nucleosidation. The process has been successfully applied to all pyrimidine and purine nucleobases.
Keywords :
modified nucleosides , psiconucleosides , 3-dipolar cycloaddition , PM3 calculation , 1
Journal title :
Tetrahedron
Journal title :
Tetrahedron
