Title of article
Efficient nucleophilic substitution reactions of pyrimidyl and pyrazyl halides with nucleophiles under focused microwave irradiation
Author/Authors
Yie-Jia Cherng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
887
To page
890
Abstract
Rapid nucleophilic displacement reactions of 2-chloropyrimidine, 2-bromopyrimidine, 5-bromopyrimidine and chloropyrazine with nucleophiles under microwave irradiation was complete within several minutes with yields up to 99%. The method using microwave irradiation is superior to the classical heating processes.
Keywords
chloropyrazine , Microwave irradiation , Nucleophilic substitution , halopyrimidines
Journal title
Tetrahedron
Serial Year
2002
Journal title
Tetrahedron
Record number
1082760
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