Title of article :
Use of lithium N,O-dimethylhydroxylamide as an efficient in situ protecting agent for aromatic aldehydes
Author/Authors :
Frank Roschangar، نويسنده , , Jennifer C Brown، نويسنده , , Bobby E. Cooley Jr.، نويسنده , , Matthew J Sharp، نويسنده , , Richard T Matsuoka، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
The use of lithium N,O-dimethylhydroxylamide as an alternative in situ protecting agent for aryl aldehydes with low ortho-directing properties has been evaluated and subsequently applied to two practical multi-step one-pot syntheses of developmental drug candidate intermediates.
Keywords :
in situ protection of aromatic aldehydes , O-dimethylhydroxylamine , N , ?-amino lithium alkoxides
Journal title :
Tetrahedron
Journal title :
Tetrahedron