Title of article :
Trifluoromethylcyclohexane as a new solvent? Limits of use
Author/Authors :
Julien Legros، نويسنده , , Benoît Crousse، نويسنده , , Daniele Bonnet-Delpon، نويسنده , , Jean-Pierre Bégué، نويسنده , , Masamichi Maruta، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
Reactivity and stability of trifluoromethylcyclohexane (TFMC) has been investigated towards various reagents, in order to evaluate its possible use as solvent. TFMC is stable in most oxidizing conditions, indicating the protective effect of a fluoroalkyl substituent towards oxidation, and surprisingly, it is also very stable towards strong bases. TFMC has also been assessed as a chlorinated solvent substitute in some reactions. It is clearly adapted as a CCl4 substitute in allylic bromination reaction.
Keywords :
hydrocarbon oxidation , selective functionnalization , trifluoromethyl compound , chlorinated solvent substitute
Journal title :
Tetrahedron
Journal title :
Tetrahedron
