Title of article :
Direct asymmetric α-hydroxylation of 2-hydroxymethyl ketones
Author/Authors :
Anne Paju، نويسنده , , T?nis Kanger، نويسنده , , T?nis Pehk، نويسنده , , Margus Lopp، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
A direct α-hydroxylation of racemic 2-hydroxymethyl ketones with the Sharpless epoxidation catalyst resulted in α,β-dihydroxy ketones in high ee (up to 97%) and in moderate to good isolated yield (up to 58%).
Keywords :
asymmetric hydroxylation , asymmetric oxidation , Sharpless complex
Journal title :
Tetrahedron
Journal title :
Tetrahedron
