The absolute configuration of polycephalin C from the slime mold Physarum polycephalum (Myxomycetes)

The absolute configuration of polycephalin C () isolated from plasmodia of the slime mold Physarum polycephalum is supposed to be 3″R,4″R as found by comparison of CD spectra of the natural product polycephalin C (1) and CD spectra of synthetic bis-benzoates and . An X-ray structure of the corresponding bis-camphanate shows that the exciton chirality method may not be applied on these 1,4-diols in the usual manner.