Enantioselective total synthesis of δ-lactonic marine natural products, (+)-tanikolide and (−)-malyngolide, via RCM reaction

Enantioselective total synthesis of δ-lactonic marine natural products, (+)-tanikolide and (−)-malyngolide isolated from Lyngbya majuscula, was achieved by using the Sharpless asymmetric epoxidation and a ring-closing metathesis, as key reactions.