Author/Authors :
P?l Tapolcs?nyi، نويسنده , , G?bor Krajsovszky، نويسنده , , R?me? And?، نويسنده , , Péter Lipcsey، نويسنده , , Gyula Horv?th، نويسنده , , Péter M?tyus، نويسنده , , Zsuzsanna Riedl، نويسنده , , Gyorgy Hajos، نويسنده , , Bert U.W. Maes، نويسنده , , Guy L.F. Lemière، نويسنده ,
Abstract :
Suzuki coupling of 5-chloro-2-methyl-6-phenylpyridazin-3(2H)-one, 6-chloro-1,3-dimethyluracil and 2-chloropyrazine with protected aminoaryl boronic acids resulted in the corresponding pivaloylaminophenyl diazines which were transformed to diazino-fused indole and cinnoline derivatives. Suzuki coupling of 5-amino-6-chloro-1,3-dimethyluracil with 2-formylphenyl boronic acid afforded a novel pyrimidoisoquinoline ring system in a one-pot reaction.
Keywords :
ring closure , Suzuki reaction , Palladium , diazines
