Title of article :
A stereoselective synthesis of squalamine
Author/Authors :
Xiang-Dong Zhou، نويسنده , , Feng Cai، نويسنده , , Wei-Shan Zhou، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
Squalamine () was synthesized stereoselectively in 14 steps and 19% overall yield from 3-keto-5α-chenodeoxycholanate () by using a modified Sharpless asymmetric dihydroxylation as the key step.
Keywords :
squalamine , improved Sharpless AD , aminosterol , Stereoselective
Journal title :
Tetrahedron
Journal title :
Tetrahedron
