Title of article
Enantioselective total synthesis of (R)-strongylodiols A and B
Author/Authors
Stefan Reber، نويسنده , , Thomas F Kn?pfel، نويسنده , , Erick Moran Carreira، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
6813
To page
6817
Abstract
We describe an expeditious enantioselective total synthesis of the acetylenic marine natural products (R)-strongylodiols A and B. Central to the strategy is the use of Zn(OTf)2, amine base, and N-methyl ephedrine to mediate the direct addition of a 1,3-diyne to two long-chain aliphatic aldehydes in useful selectivities and yields.
Keywords
Hydrocarbon , metallation , strongylodiol
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1084233
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