Title of article
An improved and practical synthesis of 5,5-dimethyl-3-(2-propoxy)-4-(4-methanesulfonylphenyl)-2-(5H)-furanone (DFP—a selective inhibitor of cyclooxygenase-2)
Author/Authors
Srinivas Padakanti، نويسنده , , Manojit Pal، نويسنده , , Koteswar Rao Yeleswarapu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
6
From page
7915
To page
7920
Abstract
DFP, a highly selective and potent COX-2 inhibitor, has been synthesized by a modified approach. Three modifications of the existing method enabled us to prepare DFP in good quantity.
Keywords
furanones , 2-isopropoxyacetic acid , anti-inflammatory agents
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1084342
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