Author/Authors :
Ryuji Yokoyama، نويسنده , , Shunji Ito، نويسنده , , Tetsuo Okujima، نويسنده , , Takahiro Kubo، نويسنده , , Masafumi Yasunami، نويسنده , , Akio Tajiri، نويسنده , , Noboru Morita، نويسنده ,
Abstract :
Amination of 2-substituted azulene was carefully examined using several types of amines, and the scope and limitation of substrates and reagents in these direct nucleophilic aminations were found. The synthesis of 2-aminoazulenes was successfully achieved by the reaction of 2-bromoazulene with several amines via palladium-catalyzed amination.
Keywords :
nucleophilic amination , 2-aminoazulene , palladium catalyzed amination , 2-bromoazulene
