Title of article :
Practical enantioselective reduction of ketones using oxazaborolidine catalyst generated in situ from chiral lactam alcohol and borane
Author/Authors :
Yasuhiro Kawanami، نويسنده , , Shinichi Murao، نويسنده , , Takahiko Ohga، نويسنده , , Nobuyo Kobayashi، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
Reduction intermediate prepared in situ from chiral lactam alcohol and borane at room temperature was found to catalyze the borane reduction of various prochiral ketones with high enantioselectivity up to 98% ee.
Keywords :
Enantioselective , Reduction , Asymmetric synthesis , lactam alcohol , Borane
Journal title :
Tetrahedron
Journal title :
Tetrahedron
