Title of article
Synthesis and glycosidase inhibitory activity of enantiopure polyhydroxylated octahydroindoles and decahydroquinolines, analogs to castanospermine
Author/Authors
Christine Gravier-Pelletier، نويسنده , , William Maton، نويسنده , , Gildas Bertho، نويسنده , , Yves Le Merrer، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
10
From page
8721
To page
8730
Abstract
The synthesis of new enantiopure polyhydroxylated octahydroindoles and decahydroquinolines, analogs to castanospermine, via a double reductive amination of enantiopure cyclic ketoaldehyde, and their inhibitory activity against α- or β-d-glucosidases, α-d-mannosidase and α-l-fucosidase are described.
Keywords
octahydroindole , Reductive amination , decahydroquinoline , glycosidase , Alkaloid , Castanospermine , bicyclic compounds , azasaccharide
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1084423
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