Title of article
Efficient production of raspberry ketone via ‘green’ biocatalytic oxidation
Author/Authors
Birgit Kosjek، نويسنده , , Wolfgang Stampfer، نويسنده , , Ruud van Deursen، نويسنده , , Kurt Faber، نويسنده , , Wolfgang Kroutil، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
9517
To page
9521
Abstract
For the development of a ‘green’ oxidation method, the transformation of 4-(p-hydroxyphenyl)butan-2-ol (rhododendrol) into 4-(p-hydroxyphenyl)butan-2-one (raspberry ketone) was used as a model reaction. Different lyophilized cells of Rhodococcus spp. have been screened for their ability to perform the desired oxidation. Rhodococcus equi IFO 3730 and R. ruber DSM 44541 were able to use acetone as a hydrogen acceptor in a hydrogen transfer-like process. The oxidation can be performed at substrate concentrations up to 500 g/L.
Keywords
Biocatalysis , Rhodococcus ruber , Oxidation , hydrogen transfer , raspberry ketone
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1084495
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