Synthesis of an enantiomerically pure 2,2,4-trisubstituted cyclobutanone building block by zirconocene-promoted deoxygenative ring contraction of structurally modified 4-vinylfuranosides

A route to an enantiopure trisubstituted cyclobutanone has been devised. The pursuit of this building block begins with d-glucose and features a zirconocene-promoted ring contraction.