Title of article
New developments in zinc-catalyzed asymmetric hydrosilylation of ketones with PMHS
Author/Authors
Virginie Bette، نويسنده , , André Mortreux، نويسنده , , Diego Savoia، نويسنده , , Jean-François Carpentier، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
6
From page
2837
To page
2842
Abstract
The influence of structural modifications of the diamine ligand and the ZnR2 precursor in the [ZnR2–diamine]-catalyzed asymmetric hydrosilylation of prochiral ketones with PMHS in aprotic medium is reported. A new diamine ligand giving up to 91% ee in the reduction of acetophenone is described. The scope of this reduction system has been investigated using variously functionalized ketones and some deactivation pathways have been identified.
Keywords
Asymmetric catalysis , Diamines , Hydrosilylation , Ketones , PMHS , zinc
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1085160
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