Title of article :
1,3-Dipolar cycloaddition of stabilised and non-stabilised azomethine ylides derived from uracil polyoxin C (UPoC): access to nikkomycin analogues
Author/Authors :
H.Ali Dondas، نويسنده , , Colin W.G. Fishwick، نويسنده , , Ronald Grigg، نويسنده , , Colin Kilner، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
Cascade thermal and decarboxylative cycloaddition reactions of uracil polyoxin C (UPoC) with mono- and di-carbonyl compounds in the presence of a dipolarophile leads, via stabilised and non-stabilised azomethine ylides respectively, to a series of polyoxin cycloadducts related to Nikkomycin B in good to excellent yields and high diastereoselectivity.
Keywords :
Calculations , Uracil polyoxin C , azomethine ylide , Nikkomycin , 3-dipolar cycloaddition , Chitin synthetase inhibitors , Decarboxylative cycloaddition , Semi-empirical , 1
Journal title :
Tetrahedron
Journal title :
Tetrahedron
