Author/Authors :
David M. Hodgson، نويسنده , , Christopher R. Maxwell، نويسنده , , Timothy J. Miles، نويسنده , , Edyta Paruch، نويسنده , , Ian R. Matthews، نويسنده , , Jason Witherington، نويسنده ,
Abstract :
The use of (−)-sparteine as an external chiral ligand in enantioselective organolithium-induced alkylative double ring-opening of dihydropyrrole epoxides and 7-azanorbornene-type epoxides gives unsaturated acyclic amino alcohols, and amino cyclohexenols in up to 87% ee.
Keywords :
organolithiums , Amino alcohols , eliminations and alkenes , Epoxides
