Title of article
Organolithium-induced enantioselective alkylative double ring-opening of epoxides: synthesis of enantioenriched unsaturated amino alcohols
Author/Authors
David M. Hodgson، نويسنده , , Christopher R. Maxwell، نويسنده , , Timothy J. Miles، نويسنده , , Edyta Paruch، نويسنده , , Ian R. Matthews، نويسنده , , Jason Witherington، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
14
From page
3611
To page
3624
Abstract
The use of (−)-sparteine as an external chiral ligand in enantioselective organolithium-induced alkylative double ring-opening of dihydropyrrole epoxides and 7-azanorbornene-type epoxides gives unsaturated acyclic amino alcohols, and amino cyclohexenols in up to 87% ee.
Keywords
organolithiums , Amino alcohols , eliminations and alkenes , Epoxides
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1085328
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