Title of article :
Synthesis of modulators of chloroquine resistance in Plasmodium falciparum, analogues of malagashanine from strychnobrasiline
Author/Authors :
François Trigalo، نويسنده , , Roger Joyeau، نويسنده , , Van Cuong Pham، نويسنده , , Jean Jacques Youté، نويسنده , , Philippe Rasoanaivoa، نويسنده , , François Frappier، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
The syntheses of three malagashanine analogues are reported. They involve conversion of strychnobrasiline in multiple steps and obtaining (i) unsaturation of the bond 3–14, (ii) inversion of configuration on carbon C3, (iii) inversion of configuration on carbon C3 and reduction of the benzene ring.
Keywords :
Strychnos myrto??des , Strychnobrasiline , Reductive amination , Alkaloid , Malagashanine
Journal title :
Tetrahedron
Journal title :
Tetrahedron
