Title of article
Synthesis of 1-benzyl-8,9-dihydroimidazo[4,5-c]pyrrolo[3,2-g]quinolin-4(5H)-one via palladium-catalyzed intramolecular arylation
Author/Authors
Bruno Delest، نويسنده , , Jean-Yves Tisserand، نويسنده , , Jean-Michel Robert، نويسنده , , Marie-Renée Nourrisson، نويسنده , , Patricia Pinson، نويسنده , , Muriel Duflos، نويسنده , , Guillaume Le Baut، نويسنده , , Pierre Renard، نويسنده , , Bruno Pfeiffer، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
6079
To page
6083
Abstract
The synthesis of a novel tetracyclic structure, 8,9-dihydroimidazo[4,5-c]pyrrolo[3,2-g]quinolin-4(5H)-one, has been achieved by a convergent pathway. Coupling of the weakly nucleophilic hindered aromatic amine with 1-benzylimidazole-4-carboxylic acid, , afforded the corresponding amide using a DCP/DMF complex; subsequent Heck-type arylation leading to desired tetracyclic molecule imidazo[4,5-c]-pyrrolo[3,2-g]quinolin-4(5H)-one.
Keywords
DCP/DMF complex , Palladium-catalyzed intramolecular arylation , 2-g]quinolin-4(5H)-one , 8 , Amide coupling
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1085808
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