Author/Authors :
Yuan Li، نويسنده , , Michael G.B. Drew، نويسنده , , Elizabeth V Welchman، نويسنده , , Rajeev K Shirvastava، نويسنده , , Shende Jiang، نويسنده , , Roy Valentine، نويسنده , , Gurdial Singh، نويسنده ,
Abstract :
The difluorinated analogues of 3-deoxy-d-arabino-heptulosonic acid (DAH) , and its enantiomer have been synthesised from d- and l-erythrose via a Reformatsky reaction which gave a mixture of diastereoiosmers in favour of the anti isomer.
Keywords :
Reformatsky reaction , Shikimate pathway , Fluorinated ulosonates , Carbohydrate , Enzyme inhibitors