Title of article :
Synthesis of 5,5′-diarylated 2,2′-bithiophenes via palladium-catalyzed arylation reactions
Author/Authors :
Aya Yokooji، نويسنده , , Tetsuya Satoh، نويسنده , , Masahiro Miura، نويسنده , , Masakatsu Nomura، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Pages :
7
From page :
6757
To page :
6763
Abstract :
2,2′-Bithiophene and 3,3′-dicyano-2,2′-bithiophenes are diarylated directly with aryl bromides at the 5- and 5′-positions accompanied by C–H bond cleavage in the presence of Pd(OAc)2 and a bulky phosphine ligand using Cs2CO3 as base. In the reaction using (2,2′-bithiophen-5-yl)diphenylmethanol as the substrate, monoarylation at the 5-position via C–C bond cleavage occurs selectively to give 5-aryl-2,2′-bithiophenes and the subsequent arylation with a different aryl bromide affords the corresponding unsymmetrically 5,5′-diarylated products.
Keywords :
aryl halides , Thiophenes , palladium and compounds , arylation
Journal title :
Tetrahedron
Serial Year :
2004
Journal title :
Tetrahedron
Record number :
1085873
Link To Document :
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