Title of article
Development of β-hydroxyamide/titanium complexes for catalytic enantioselective silylcyanation of aldehydes
Author/Authors
Biing-Jiun Uang، نويسنده , , Hsin-Pin Fu، نويسنده , , Chyuan-Der Hwang، نويسنده , , Chun-Wei Chang، نويسنده , , Chun-Tzu Yang، نويسنده , , Der-Ren Hwang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
8
From page
10479
To page
10486
Abstract
A highly enantioselective addition of trimethylsilylcyanide to aldehydes catalyzed by chiral titanium complexes is described. The chiral titanium complexes were prepared in situ from Ti(OiPr)4 and β-hydroxyamide ligands, that could easily be synthesized from ketopinic acid and C2 symmetrical chiral diamines in a small number of steps.
Keywords
Titanium complex , ?-Hydroxyamide , Asymmetric catalysis , cyanohydrin
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1087259
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