Title of article
Enzymatic acylation reactions on ω-hydroxycyanohydrins
Author/Authors
Gonzalo de Gonzalo، نويسنده , , Iv?n Lavandera، نويسنده , , Rosario Brieva، نويسنده , , Vicente Gotor، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
8
From page
10525
To page
10532
Abstract
The enzymatic acylation of certain ω-hydroxycyanohydrins protected at the primary alcohol has been studied. The best enantioselectivities are obtained with Pseudomonas cepacia lipase (PSL-C) and Candida antarctica lipase A (CAL-A), for the ω-O-tritylated cyanohydrins. The effect of the protecting group in the enzymatic reactions has been studied using molecular modeling.
Keywords
Molecular modeling , Lipase catalyzed acetylation , Cyanohydrins
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1087265
Link To Document