Author/Authors :
Ashley W. Jones، نويسنده , , Bambang Purwono، نويسنده , , Paul K. Bowyer، نويسنده , , Peter S.R. Mitchell، نويسنده , , Naresh Kumar، نويسنده , , Stephen J. Nugent، نويسنده , , Katrina A. Jolliffe، نويسنده , , David StC. Black، نويسنده ,
Abstract :
A range of 3-substituted-4,6-dimethoxyindoles bearing electron-withdrawing groups in either the 2- or 7-position, can be nitrated using nitric acid adsorbed on silica, to give 7-nitro and 2-nitro-indoles, respectively. A 1-cyano-indole gives regioselectively the 2-nitro-indole with loss of the cyano group.
