Author/Authors :
Chiara Danieli، نويسنده , , Franco Ghelfi، نويسنده , , Adele Mucci، نويسنده , , Ugo M. Pagnoni، نويسنده , , Andrew F. Parsons، نويسنده , , Mariella Pattarozzi، نويسنده , , Luisa Schenetti، نويسنده ,
Abstract :
The reaction of 4-methyl-pyrrolidin-2-ones, chlorinated at the C(3) and C(6) positions, with n-propylamine constitutes a new method for the preparation of 5-propylimino-pyrrolidin-2-ones or 3-pyrrolin-2-ones in generally good yields. The transformation involves a series of eliminations, substitutions and double bond shifts. This constitutes a remarkable example of a functional rearrangement.
Keywords :
Radical reactions , pyrrolidinones , rearrangements , N-Nucleophiles
