Title of article
Synthesis and antitumor activity of 2-(m-substituted-benzoyl)baccatin III analogs from taxinine
Author/Authors
Tohru Horiguchi، نويسنده , , Takayuki Oritani، نويسنده , , Hiromasa Kiyota، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
10
From page
1529
To page
1538
Abstract
2-m-Azidobenzoyl and 2-m-chlorobenzoyl baccatin III analogs were prepared from taxinine, a major component in Japanese yew leaves. In this study, a novel acetyl migration from 13- to 4-hydroxyl group was observed. The antitumor activity of these compounds was evaluated.
Keywords
Taxol , Antitumor activity , taxinine , m-azidobenzoyl
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1087566
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