• Title of article

    Synthesis and antitumor activity of 2-(m-substituted-benzoyl)baccatin III analogs from taxinine

  • Author/Authors

    Tohru Horiguchi، نويسنده , , Takayuki Oritani، نويسنده , , Hiromasa Kiyota، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    10
  • From page
    1529
  • To page
    1538
  • Abstract
    2-m-Azidobenzoyl and 2-m-chlorobenzoyl baccatin III analogs were prepared from taxinine, a major component in Japanese yew leaves. In this study, a novel acetyl migration from 13- to 4-hydroxyl group was observed. The antitumor activity of these compounds was evaluated.
  • Keywords
    Taxol , Antitumor activity , taxinine , m-azidobenzoyl
  • Journal title
    Tetrahedron
  • Serial Year
    2003
  • Journal title
    Tetrahedron
  • Record number

    1087566