Author/Authors :
Stéphane Guillarme، نويسنده , , Stéphanie Legoupy، نويسنده , , Anne-Marie Aubertin، نويسنده , , Cécile Olicard، نويسنده , , Nathalie Bourgougnon، نويسنده , , François Huet، نويسنده ,
Abstract :
The synthesis of several acyclic nucleosides and , analogs of penciclovir, was achieved by Michael addition as the key step. This reaction worked not only for the protected natural bases but even for the less nucleophilic deaza purine and deaza pyrimidine.
Keywords :
acyclic nucleosides , deaza purine and deaza pyrimidine , analogs of penciclovir , Michael addition
