• Title of article

    Synthesis of enantiopure 3-amino-1-azaspiro[4.5]decan-8-ones by halonium promoted cyclization of amino-tethered cyclohexenes

  • Author/Authors

    Gemma Puigb?، نويسنده , , Fa??za Diaba، نويسنده , , Josep Bonjoch، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    9
  • From page
    2657
  • To page
    2665
  • Abstract
    Haloaminocyclization reactions of polysubstituted γ-aminocyclohexenes give 3-amino-1-azaspiro[4.5]decan-8-one derivatives. The stereocontrol, chemoselectivity (N-attack vs O-attack), and influence of the halonium ion are discussed.
  • Keywords
    azaspiro compounds , Nitrogen heterocycles , FR901483 , Cyclization , oxazines
  • Journal title
    Tetrahedron
  • Serial Year
    2003
  • Journal title
    Tetrahedron
  • Record number

    1087683