Title of article
Synthesis of enantiopure 3-amino-1-azaspiro[4.5]decan-8-ones by halonium promoted cyclization of amino-tethered cyclohexenes
Author/Authors
Gemma Puigb?، نويسنده , , Fa??za Diaba، نويسنده , , Josep Bonjoch، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
9
From page
2657
To page
2665
Abstract
Haloaminocyclization reactions of polysubstituted γ-aminocyclohexenes give 3-amino-1-azaspiro[4.5]decan-8-one derivatives. The stereocontrol, chemoselectivity (N-attack vs O-attack), and influence of the halonium ion are discussed.
Keywords
azaspiro compounds , Nitrogen heterocycles , FR901483 , Cyclization , oxazines
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1087683
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