Author/Authors :
Asish K. Bhattacharya، نويسنده , , Mahesh Pal، نويسنده , , Dharam C Jain، نويسنده , , Bhawani S Joshi، نويسنده , , Raja Roy، نويسنده , , Urszula Rychlewska، نويسنده , , Ram P Sharma، نويسنده ,
Abstract :
Absolute stereochemistry of dihydroarteannuin B obtained by the reduction of arteannuin B with Ni2B, NaBH4 or CdCl2–Mg–MeOH–H2O has been established by 2D NMR and single crystal X-ray diffraction studies. Some experiments aimed at the synthesis of dihydrodeoxyarteannuin B [C-4, 5 double bond isomer of ] are also discussed.
Keywords :
arteannuin B , chemical transformations , Artemisia annua , Artemisinin , antimalarial
