Title of article
Isoxazolidine analogues of pseudouridine: a new class of modified nucleosides
Author/Authors
Ugo Chiacchio، نويسنده , , Antonino Corsaro، نويسنده , , Juan Mates، نويسنده , , Pedro Merino، نويسنده , , Anna Piperno، نويسنده , , Antonio Rescifina، نويسنده , , Giovanni Romeo، نويسنده , , Roberto Romeo، نويسنده , , Tomas Tejero، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
6
From page
4733
To page
4738
Abstract
A new class of modified C-nucleosides has been synthesized according to the 1,3-dipolar cycloaddition methodology. The obtained compounds are structurally related to natural pseudouridine, where the sugar moiety is replaced by an isoxazolidine ring. Different experimental conditions, and the effect of additives on the cycloaddition process, have been examined; the best results were obtained when the cycloaddition reaction was performed under microwave irradiation
Keywords
Cycloaddition , Pseudouridine , Glycosidic bond
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1087892
Link To Document