Title of article
Difluorinated analogues of shikimic acid
Author/Authors
Lovely Begum، نويسنده , , Julian M Box، نويسنده , , Michael G.B. Drew، نويسنده , , Laurence M. Harwood and others، نويسنده , , Jane L Humphreys، نويسنده , , David J Lowes، نويسنده , , Gareth A Morris، نويسنده , , Perrine M Redon، نويسنده , , Francine M Walker، نويسنده , , Roger C. Whitehead، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
15
From page
4827
To page
4841
Abstract
Investigations into the quinate to shikimate transformation have been carried out, the results of which have been exploited in the synthesis of a novel difluoromethylene homologue of shikimic acid from (−)-quinic acid. Martinʹs sulfurane {Ph2S[OC(CF3)2Ph]2} was the reagent of choice for the key dehydration step of this synthesis. The results of investigations into the synthesis of the important natural product analogue, 6,6-difluoroshikimic acid are also reported.
Keywords
Martinיs sulfurane , Fluorinated analogues , Shikimic acid
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1087905
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