• Title of article

    Synthesis of an external beta-turn based on the GLDV motif of cell adhesion proteins

  • Author/Authors

    David E. Davies، نويسنده , , Paul M. Doyle، نويسنده , , Richard D. Hill، نويسنده , , Douglas W. Young، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2005
  • Pages
    12
  • From page
    301
  • To page
    312
  • Abstract
    The (3S,6S,10S)-7/5 bicyclic lactam , designed as an external turn constraint, was synthesised by a new stereoselective route involving Eschenmoser condensation. The cyclic peptide containing the integrin recognition motif GLDV added across the amino and carboxyl groups of the lactam external constraint was prepared.
  • Keywords
    Integrin , Eschenmoser olefination , bicyclic lactam
  • Journal title
    Tetrahedron
  • Serial Year
    2005
  • Journal title
    Tetrahedron
  • Record number

    1088253