Author/Authors :
Alessandro Mordini، نويسنده , , Daniela Peruzzi، نويسنده , , Francesco Russo، نويسنده , , Michela Valacchi، نويسنده , , Gianna Reginato، نويسنده , , Alberto Brandi، نويسنده ,
Abstract :
Aryl- and alkenyl substituted oxiranes, when submitted to treatment with superbasic reagents, undergo a highly regio- and stereoselective rearrangement leading to cyclopropylmethanol derivatives. The process can also be applied to mono- and dihydroxy substituted substrates thus leading to polyhydroxylated cyclopropanes.
Keywords :
Cyclopropanes , rearrangement , 3-exo Cyclization , Superbase
