Author/Authors :
Fumihiro Nagashima، نويسنده , , Masuo Kondoh، نويسنده , , Makiko Fujii، نويسنده , , Shigeru Takaoka، نويسنده , , Yoshiteru Watanabe، نويسنده , , Yoshinori Asakawa، نويسنده ,
Abstract :
Novel cytotoxic rearranged kaurene- and ent-kaurene-type diterpenoids against HL-60 cells have been isolated from the unidentified New Zealand liverwort Jungermannia species together with previously known ent-kaurane-type diterpenoids. Their structures were determined by extensive NMR techniques, chemical degradation and X-ray crystallographic analysis.
Keywords :
Kaurane-type diterpenoid , liverwort , Jungermannia , Cytotoxic