Title of article :
Electron deficiency of aldehydes controls the pyrrolidine catalyzed direct cross-aldol reaction of aromatic/heterocyclic aldehydes and ketones in water
Author/Authors :
Swapandeep Singh Chimni، نويسنده , , Dinesh Mahajan، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
A synthetically useful pyrrolidine catalyzed direct cross-aldol reaction of aromatic/heterocyclic aldehydes with ketones in water affords the aldol addition product in up to 93% yield. Electrophilicity of the aldehydes controls the course of the reaction.
Keywords :
Cross-aldol , Pyrrolidine catalysis , ?-hydroxy ketones , Aqueous medium , Heterocyclic aldol
Journal title :
Tetrahedron
Journal title :
Tetrahedron
