A novel method for synthesis of arylacetic acids from aldehydes, N-(2,3,4,6-tetra-O-pivaloylated-d-glucopyranosyl)amine and trimethylsilylcyanide

A novel synthetic approach for the preparation of arylacetic acids via the reaction of aldehydes, N-(2,3,4,6-tetra-O-pivaloylated-d-glucopyranosyl)amine and trimethylsilylcyanide was developed, in which the N-(2,3,4,6-tetra-O-pivaloylated-d-glucopyranosyl)amine can be recycled conveniently and reused efficiently.