• Title of article

    Palladium-catalyzed sequential alkylation–alkenylation reactions: application towards the synthesis of polyfunctionalized fused aromatic rings

  • Author/Authors

    Dino Alberico، نويسنده , , Jean-François Paquin، نويسنده , , Mark Lautens، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2005
  • Pages
    15
  • From page
    6283
  • To page
    6297
  • Abstract
    The synthesis of polyfunctionalized fused aromatic carbo- and heterocycles from aryl iodides and bromoenoates via a tandem palladium-catalyzed aromatic substitution intramolecular Heck sequence is reported. Using Pd(OAc)2 and tri-2-furylphosphine (TFP) in the presence of norbornene and Cs2CO3 in CH3CN at 85 °C gave a variety of functionalized bi- and tricyclic fused aromatic rings in good yield.
  • Keywords
    Catalysis , intramolecular Heck reaction , Catellani reaction , ortho Functionalization , Fused aromatic rings , Palladium , Norbornene
  • Journal title
    Tetrahedron
  • Serial Year
    2005
  • Journal title
    Tetrahedron
  • Record number

    1088845

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1088845