Author/Authors :
Anna Aiello، نويسنده , , Monica DʹEsposito، نويسنده , , Ernesto Fattorusso، نويسنده , , Marialuisa Menna، نويسنده , , Werner E.G. Muller، نويسنده , , Sanja Perovi?-Ottstadt، نويسنده , , Hideyuki Tsuruta، نويسنده , , Tobias A.M. Gulder، نويسنده , , Gerhard Bringmann، نويسنده ,
Abstract :
The isolation and characterization of the known pyrrole alkaloid agelongine () and of the new natural product daminin (), the bromine-free analogue of , from a specimen of the marine sponge Axinella damicornis is described. Compound showed significant neuroprotective properties. Moreover, for the supply of sufficient material for future medicinal investigations, a short total synthesis of was developed.
Keywords :
Sponges , Pyrrole alkaloids , marine natural products , Total synthesis
