• Title of article

    Bisphosphonate prodrugs: synthesis of new aromatic and aliphatic 1-hydroxy-1,1-bisphosphonate partial esters

  • Author/Authors

    Maelle Monteil، نويسنده , , Erwann Guenin، نويسنده , , Evelyne Migianu، نويسنده , , Didier Lutomski، نويسنده , , Marc Lecouvey، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2005
  • Pages
    10
  • From page
    7528
  • To page
    7537
  • Abstract
    Methods for the preparation of various 1-hydroxy-1,1-bisphosphonate partial esters were developed. They were obtained from (alkyl or phenyl) bis(trimethylsilyl) phosphite and aromatic or aliphatic acid chlorides, followed by methanolysis.
  • Keywords
    bisphosphonate , Arbusov reaction
  • Journal title
    Tetrahedron
  • Serial Year
    2005
  • Journal title
    Tetrahedron
  • Record number

    1088973