Author/Authors :
Venkateswara Rao Batchu، نويسنده , , Venkataraman Subramanian، نويسنده , , Karuppasamy Parasuraman، نويسنده , , Nalivela Kumara Swamy، نويسنده , , Sanjeev Kumar، نويسنده , , Manojit Pal، نويسنده ,
Abstract :
2-Aminoethanol facilitated the alkynylation of aryl halides (Sonogashira reaction) under palladium/charcoal–copper catalysis in water affording a mild and practical method for the synthesis of arylalkynes. A variety of terminal alkynes were coupled with aryl iodides and bromides possessing no hydrophilic functional groups to give the coupled products in good to excellent yields.
Keywords :
Palladium catalyst , 2-Aminoethanol , aryl halides , Aqueous media
