New enantioselective method for hydration of alkenes using cyclodextrins as phase transfer catalyst

A new enantioselective/inverse phase transfer catalysis (IPTC) reaction for the Markovnikov hydration of double bounds by an oxymercuration–demercuration reaction with cyclodextrins as catalysts was disclosed. Moderate ee (up to 32%) and yields (14–60%) were obtained for allylic amines and protected allylic alcohols as starting materials.