Title of article
Three new sulfur-containing alkaloids, polycarpaurines A, B, and C, from an Indonesian ascidian Polycarpa aurata
Author/Authors
Weifang Wang، نويسنده , , Taiko Oda، نويسنده , , Ayako Fujita، نويسنده , , Remy E.P. Mangindaan، نويسنده , , Takahiro Nakazawa، نويسنده , , Kazuyo Ukai، نويسنده , , Hisayoshi Kobayashi، نويسنده , , Michio Namikoshi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
409
To page
412
Abstract
Three new sulfur-containing alkaloids, polycarpaurines A (1), B (2), and C (3) were isolated from the tropical ascidian Polycarpa aurata collected in Indonesia, together with six known compounds (4–9). The structures of new compounds were assigned on the basis of their spectral data. Compounds 1, 3, 4, and 8 inhibited colony formation of Chinese hamster V79 cells with EC50 values of 6.8, 8.6, 3.8, and 10 μM, respectively. Compounds 2 and 7 showed modest activity against V79 cells (EC50>10 μM).
Keywords
Structure assignment , Sulfur-containing alkaloid , Polycarpa aurata , ascidian , Polycarpaurine
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1090038
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