Author/Authors :
Antonio de la Hoz، نويسنده , , J.E. Angel-Diaz، نويسنده , , José Elguero، نويسنده , , Agust?n Jiménez، نويسنده , , Andrés Moreno، نويسنده , , Amparo Ruiz، نويسنده , , Ana S?nchez-Migall?n، نويسنده ,
Abstract :
We describe the preparation of 1,4′-bipyrazolyls and 4-pyrazolylpyrimidines by the reaction of 2-pyrazolyl-3-dimethylamino acrylate and acrylonitrile with double nucleophilic reagents such as hydrazines, urea and guanidine. Reactions were performed under microwave irradiation in 5–60 min. This is a useful procedure for the preparation of valuable compounds with applications in medicinal and coordination chemistry.
