Title of article
Synthesis of DMJ analogs with seven- and eight-membered iminocyclitols
Author/Authors
Meng-Yang Chang، نويسنده , , Yung-Hua Kung، نويسنده , , Chih-Chong Ma، نويسنده , , Shui-Tein Chen، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
6
From page
1339
To page
1344
Abstract
A straightforward synthesis of new hydroxy azepane and azocane with an additional hydroxymethyl side arm (1-deoxymannojirimycin, DMJ analogs) has been achieved from trans-(2S,4R)-4-hydroxyproline via Grignard addition, ring-closing metathesis, and stereoselective osmylation as the key steps.
Keywords
1-Deoxymannojirimycin (DMJ) , Azepane , Azocane , Ring-closing metathesis , Stereoselective osmylation , Grignard addition , trans-(2S , 4R)-4-Hydroxyproline
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1090213
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