Title of article :
Synthesis of novel 5,6-substituted furo[2,3-d]pyrimidines via Pd-catalyzed cyclization of alkynylpyrimidinols with aryl iodides
Author/Authors :
Zhende Liu، نويسنده , , Dewen Li، نويسنده , , Shukun Li، نويسنده , , Donglu Bai، نويسنده , , Xuchang He، نويسنده , , Youhong Hu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
A flexible method for the synthesis of 5,6-disubstituted furo[2,3-d]pyrimidine derivatives is described. The key step is a palladium-catalyzed arylative cyclization of alkynylpyrimidinols with various aryl iodides, which gave the title compounds in 36–75% yield.
Keywords :
3-d]pyrimidines , Sonogashira coupling reaction , Palladium-catalyzed cyclization
Journal title :
Tetrahedron
Journal title :
Tetrahedron
