Author/Authors :
Nigel Ribeiro، نويسنده , , Stéphane Streiff، نويسنده , , Denis Heissler، نويسنده , , Mourad Elhabiri، نويسنده , , Anne Marie Albrecht-Gary، نويسنده , , Michiko Atsumi، نويسنده , , Mari Gotoh، نويسنده , , Laurent Désaubry، نويسنده , , Yoichi Nakatani، نويسنده , , Guy Ourisson، نويسنده ,
Abstract :
Cholesterol plays the role of membrane reinforcer in eukaryotes, whereas hopanoids play the same role in bacteria. Which components could have reinforced ‘primitive’ membranes? We describe here an efficient biomimetic synthesis of bi- and tri-cyclopolyprenols and demonstrate that these compounds reinforce the membranes of polyprenyl phosphate, which we speculated as ‘primitive’ membranes.
Keywords :
Lipids , Biomimetic synthesis , Terpenes , Membranes
